The Susies are a gang of assassins that formed somewhere in Asia. At some point before 1979, they moved to Champion City and caught the attention of the supervillain Casanova Frankenstein, who allows them to join his organization as a part of his plan to unite all organized crime groups in Champion City together under his rule. They remained with his organization until his incarceration in a mental institution in 1979. In 1999, the Susies attend a meeting held by the recently paroled Casanova Frankenstein intended to reunite his former gangs and to demonstrate his new weapon for them. They witness the end results of the machine's power after they are shown Captain Amazing's dead body. During a final attack on Casanova's mansion by the Mystery Men, they are defeated by The Spleen and Invisible Boy. It is unknown whether or not they survived the destruction of Casanova's mansion.
- Guns: The Susies all carry custom handguns and shotguns. They were disarmed by the Mystery Men's Electro-Nuclear Magnet.